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health:disease_manual:rstarvation_syndrome [2024/06/19 18:26]
ron [Control and Treatment] | health:disease_manual:rstarvation_syndrome [2024/06/20 09:31] (current)
ron [Control and Treatment] |
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| The cause of SS is often unknown as the fish present with no other obvious pathologic conditions. Similar changes are seen in the intestine in severely immune compromised humans with AIDS or Common Immune Deficiency Syndrome, suggesting that an idiopathic immunosuppression agent should be considered. Anorexia is probably an important component of SS, but we have seen that simple fasting, even for a month, does not induce the disease. | The cause of SS is often unknown as the fish present with no other obvious pathologic conditions. Similar changes are seen in the intestine in severely immune compromised humans with AIDS or Common Immune Deficiency Syndrome, suggesting that an idiopathic immunosuppression agent should be considered. Anorexia is probably an important component of SS, but we have seen that simple fasting, even for a month, does not induce the disease. |
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| Figure 1. Liver and intestine of fish with Starvation Syndrome (SS) compared to normal. H&E. A. Liver of fish with SS. Note greatly reduced cytoplasm to nucleus ratio in all hepatocytes. Bar = 20 µm. B. Liver from normal male, with more prominent cytoplasm in hepatocytes. C. Liver from normal female, with typically more basophilic cytoplasm compared to males. D, E. Intestines of two fish with SS. Note reduced height of intestinal plates and prominent, diffuse, chronic inflammation of underlying lamina propria (LP). Bar = 50 µm. F. Intestine from normal fish with prominent intestinal plates. | **Figure 1. Liver and intestine of fish with Starvation Syndrome (SS) compared to normal. H&E. A. Liver of fish with SS. Note greatly reduced cytoplasm to nucleus ratio in all hepatocytes. Bar = 20 µm. B. Liver from normal male, with more prominent cytoplasm in hepatocytes. C. Liver from normal female, with typically more basophilic cytoplasm compared to males. D, E. Intestines of two fish with SS. Note reduced height of intestinal plates and prominent, diffuse, chronic inflammation of underlying lamina propria (LP). Bar = 50 µm. F. Intestine from normal fish with prominent intestinal plates.** |
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| {{ :health:disease_manual:ss_liver_and_gut_correct.jpg?nolink |}} | {{ :health:disease_manual:ss_liver_and_gut_correct.jpg?nolink |}} |
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| Figure 2. Ovary and muscle of fish with Starvation Syndrome and normal fish. H&E. A. Atrophy of the ovary in a fish with SS. Note only immature oocytes and no vitellogenic eggs. Bar = 100 µm. B. Normal ovary (lower magnification), replete with large, eosinophilic, vitellogenic eggs. C. Diffuse myodegeneration and myositis in fish with SS. Bar = 50 µm. D. Normal muscle. | **Figure 2. Ovary and muscle of fish with Starvation Syndrome and normal fish. H&E. A. Atrophy of the ovary in a fish with SS. Note only immature oocytes and no vitellogenic eggs. Bar = 100 µm. B. Normal ovary (lower magnification), replete with large, eosinophilic, vitellogenic eggs. C. Diffuse myodegeneration and myositis in fish with SS. Bar = 50 µm. D. Normal muscle.** |
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| {{ :health:disease_manual:ss_muscle_and_ovary_correct_b.jpg?nolink |}} | {{ :health:disease_manual:ss_muscle_and_ovary_correct_b.jpg?nolink |}} |
